Diagnostic approach to Thrombocytopenia

Platelets < 150,000 /µl

Isolated thrombocytopenia platelets < 100,000/ µl

Blood Smear

Platelet clumps

Repeat CBC in tube with heparin or citrate

Pseudothrombocytopenia

Evaluate for: infection connective tissue disease medications AND Consider referral to Hematologist

Repeat every 6-12 months

Periodic CBC